| Guinness Premiership |
| Sun 06 Sept 2009 | Northampton - Worcester | 20-17 |
|
| Sat 12 Sept 2009 | Saracens - Northampton | 19-16 (B) |
|
| Sat 19 Sept 2009 | Gloucester - Northampton | 14-27 |
|
| Sat 26 Sept 2009 | Northampton - Leeds | (B) 30-10 |
|
| Sun 04 Oct 2009 | Wasps - Northampton | 20-15 (B) |
|
| Sat 24 Oct 2009 | Northampton - Sale | 21-16 |
|
| Sat 31 Oct 2009 | Leicester - Northampton | 29-15 |
|
| Sat 21 Nov 2009 | Northampton - Harlequins | 26-17 |
|
| Fri 27 Nov 2009 | Newcastle - Northampton | 8-28 |
|
| Sat 05 Dec 2009 | Northampton - Bath | 15-13 |
|
| Sat 26 Dec 2009 | Worcester - Northampton | 6-26 |
|
| Sat 02 Jan 2010 | Northampton - London Irish | 24-22 |
|
| Sat 13 Feb 2010 | Northampton - Newcastle | 25-13 |
|
| Sat 20 Feb 2010 | Harlequins - Northampton | 13-6 (B) |
|
| Sat 27 Feb 2010 | Northampton - Leicester | 19-3 |
|
| Sun 07 Mar 2010 | Sale - Northampton | 7-15 |
|
| Sat 27 Mar 2010 | Northampton - Wasps | |
|
| Sun 04 Apr 2010 | Leeds - Northampton | |
|
| Sat 17 Apr 2010 | Northampton - Gloucester | |
|
| Tue 20 Apr 2010 | Bath - Northampton | |
|
| Sat 24 Apr 2010 | Northampton - Saracens | |
|
| Sat 08 May 2010 | London Irish - Northampton | |
|
